When a dog is diagnosed with an incurable condition such as heart failure or an enlarged heart, it is natural for owners to wonder what the future holds and how long their dog may live. Fortunately, several clinical studies on dog heart disease life expectancy provide helpful guidance. Still, it is essential to remember that every dog is an individual, and prognosis depends on many factors, including the underlying disease, response to treatment, and overall health.
Life Expectancy in Dogs With Enlarged Hearts Due to Leaky Heart Valves
A leaky heart valve—medically known as mitral valve disease (mitral valve endocardiosis)—is the most common form of heart disease in dogs. It affects up to 75% of dogs, especially small breeds. Fortunately, not all affected dogs ever develop clinical symptoms.
Mitral valve disease is progressive and incurable, but modern medications can slow disease progression and control symptoms. With appropriate treatment, many dogs maintain a good quality of life for an extended period. More detailed information on treatment options is available in separate articles and in my book.

What Is the Life Expectancy for Dogs With Mitral Valve Disease?
With Fluid in the Lungs (Congestive Heart Failure – Stage C and Beyond)
When evaluating life expectancy in dogs with heart disease, it is critical to determine whether the dog has entered congestive heart failure. Heart failure means the dog currently has, or has previously had, fluid in the lungs.
Clinical studies show that once heart failure develops, the average survival time is approximately 260 days when treated with pimobendan, furosemide, and possibly ACE inhibitors and/or spironolactone. This represents an average: some dogs may live only days or weeks, while others survive more than two years.
Overall, after the onset of heart failure, a life expectancy of about 9 to 12 months is a realistic estimate for many dogs.
Without Fluid in the Lungs (Preclinical Stages B1 and B2)
If a dog has not yet developed heart failure, it may take several years before symptoms appear. At this stage, prognosis depends largely on how early the disease is diagnosed.
The most accurate assessments come from repeated cardiac ultrasounds, which allow veterinarians to monitor changes over time. A large, well-known study evaluated the effect of pimobendan (Vetmedin) in dogs with heart enlargement but no clinical signs, comparing treated dogs to a placebo group.
The results were striking. Dogs treated with pimobendan developed heart failure or experienced cardiac-related death after an average of 3.2 years, which was approximately 15 months longer than dogs that did not receive the medication. This clearly demonstrates the importance of early diagnosis and timely treatment.
If the disease is diagnosed later—such as when a dog begins coughing—a significant portion of the preclinical phase may already have passed, shortening the remaining time before heart failure.
On average:
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With pimobendan: ~3.2 years from diagnosis of heart enlargement to heart failure
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Without pimobendan: ~2 years
Life Expectancy in Dogs With Enlarged Hearts Due to Dilated Cardiomyopathy (DCM)
Large and giant breeds are more likely to develop dilated cardiomyopathy (DCM). In this disease, the heart muscle weakens and gradually loses its ability to pump blood effectively. Over time, this can lead to fluid buildup in the lungs and dangerous heart rhythm disturbances.
In the asymptomatic (preclinical) stage of DCM, pimobendan (Vetmedin) is the most important medication. A recent study in Doberman Pinschers showed that dogs treated with pimobendan lived significantly longer—an average of 623 days, compared to 466 days in untreated dogs.
Another study involving Irish Wolfhounds found that dogs receiving pimobendan survived approximately 65 months before developing heart failure or experiencing sudden cardiac death—nearly twice as long as dogs treated with other medications alone.
Clinical experience suggests that dogs with early-detected, asymptomatic DCM may remain symptom-free for 2 to 4 years. However, there is always a risk of sudden cardiac death, particularly with this disease.
Once heart failure develops, survival time is typically 6 to 12 months.
Summary: Life Expectancy in Dogs With DCM
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Asymptomatic stage: approximately 2–4 years
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After heart failure develops: typically 6–12 months
Factors That Affect Life Expectancy in Dogs With Heart Disease
Several factors can significantly influence prognosis and life expectancy:
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Other medical conditions: Diseases such as kidney failure can limit treatment options and worsen outcomes.
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Breed: Certain breeds experience faster disease progression, such as the Cavalier King Charles Spaniel with mitral valve disease.
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Medication compliance: Some dogs resist taking multiple daily medications, making optimal treatment challenging.
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Weight and muscle loss: Loss of muscle mass in advanced stages is associated with a poorer prognosis.
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Fainting episodes and sudden cardiac death: Syncope indicates a more serious condition. Dogs with DCM are especially at risk.
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Owner awareness and response: Owners who notice changes early and seek prompt veterinary care can often stabilize their dog sooner. Monitoring resting respiratory rate at home is particularly important.
Effect of pimobendan or benazepril hydrochloride on survival times in dogs with congestive heart failure caused by naturally occurring myxomatous mitral valve disease: the QUEST study. J Vet Intern Med. 2008 Sep-Oct;22(5):1124-35. doi: 10.1111/j.1939-1676.2008.0150.x. Epub 2008 Jul 11.
Clinical efficacy of pimobendan versus benazepril for the treatment of acquired atrioventricular valvular disease in dogs.J Am Anim Hosp Assoc. 2006 Jul-Aug;42(4):249-61.
Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial. J Vet Intern Med. 2016 Nov;30(6):1765-1779. doi: 10.1111/jvim.14586. Epub 2016 Sep 28.
Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in Doberman Pinschers with preclinical dilated cardiomyopathy (the PROTECT Study). J Vet Intern Med. 2012 Nov-Dec;26(6):1337-49. doi: 10.1111/j.1939-1676.2012.01026.x. Epub 2012 Oct 18.



